Course

Immunology: Autoimmunity, Allergy, and Transplants

Imperial College London

In this comprehensive course, delve into the intricate mechanisms and immune responses involved in autoimmune diseases, allergies, and transplant rejection. Explore the potential causes and factors contributing to an overactive immune system, leading to disorders if not adequately controlled. Gain a deeper understanding of the consequences of an imbalance between effector and regulatory immune responses, as well as the potential mechanisms behind autoimmunity in common autoimmune conditions.

Uncover the exaggerated and unnecessary immune reactions to innocuous particles observed in allergies and hypersensitivity reactions in asthma. Additionally, analyze the effects of overactive immune responses in transplant rejection, examining the various types of transplantation and host versus graft reactions.

Through its structured modules, this course offers in-depth insights into systemic lupus erythematosus, haematological autoimmune conditions, asthma, allergic reactions, and antibody-mediated transplant rejection. Engage with rich content, including practice quizzes, to reinforce your understanding and application of the vital concepts covered in this course.

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Immunology: Autoimmunity, Allergy, and Transplants
Course Modules

Immunology: Autoimmunity, Allergy, and Transplants offers a structured exploration of autoimmune diseases, allergies, and transplant rejection. From understanding immune tolerance mechanisms to examining exaggerated immune reactions, each module provides valuable insights into this complex field.

Introduction to autoimmunity

Module 1 introduces the fundamentals of autoimmunity, covering immune tolerance mechanisms and their failure. Gain insights into the potential causes and factors behind overactive immune responses and the disorders that may ensue if not controlled. Engage with the course introduction and delve into the intricate relationship between human endogenous retroviruses and multiple sclerosis.

Systemic lupus erythematosus (SLE)

Module 2 focuses on systemic lupus erythematosus (SLE), providing an in-depth understanding of SLE pathogenesis, causes, and risk factors. Explore the complexities of this autoimmune condition and reinforce your knowledge with practice quizzes.

Haematological autoimmune conditions

Module 3 delves into haematological autoimmune conditions, including immune thrombocytopenia, autoimmune haemolytic anaemia, and other related disorders. Gain a comprehensive understanding of these conditions and their implications.

Asthma and allergic reactions

Module 4 explores asthma and allergic reactions, covering inappropriate immune responses, T follicular helper cells in allergy and asthma, factors initiating asthma, mechanisms of action, and the various classes of hypersensitivity. Additionally, assess your knowledge through practice quizzes.

Antibody-mediated transplant rejection

Module 5 provides detailed insights into antibody-mediated transplant rejection, addressing tissue transplant and the immune system, types of transplantation, host versus graft reactions, types of graft rejection, and graft versus host disease (GvHD). Expand your understanding of transplant rejection mechanisms and implications.

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