Course

Bioconductor for Genomic Data Science

Johns Hopkins University

Explore the world of genomic data analysis with this in-depth course from Johns Hopkins University. Discover the power of Bioconductor tools as you delve into topics such as R installation, Bioconductor usage, data types, and advanced analysis techniques.

Throughout the course, you'll gain practical insights into working with Bioconductor packages, including Biostrings, BSgenome, GenomicRanges, and more. By the end, you'll have a solid understanding of genomic data science and the Bioconductor project's role in advancing this field.

  • Learn to install R and R Studio on various platforms
  • Understand the fundamentals of Bioconductor and its website
  • Explore data types, genomic features, and advanced analysis methods
  • Discover how to import and work with different types of genomic data

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Bioconductor for Genomic Data Science
Course Modules

This course comprises four modules covering a range of topics. From installation and basic concepts to advanced analysis methods, each module offers valuable insights into genomic data science.

Week One

Week One introduces you to the fundamental concepts of Bioconductor and R installation. You'll explore R base types, GRanges, IRanges, GenomicRanges, and AnnotationHub. By the end of this module, you'll have a solid foundation for working with Bioconductor tools.

Week Two

Week Two delves into more advanced topics, including Biostrings, BSgenome, GenomicRanges, and rtracklayer. Through practical examples and insights, you'll gain a deeper understanding of these essential Bioconductor packages and their applications in genomic data science.

Week Three

Week Three focuses on basic data types, genomic features, and data import methods through Annotation Overview, ExpressionSet, GEOquery, and biomaRt. You'll also explore R S4 classes and methods, gaining a comprehensive understanding of these concepts.

Week Four

Week Four covers the crucial aspect of getting data into Bioconductor, including Short Read, Rsamtools, oligo, limma, and minfi. Additionally, you'll delve into count-based RNA-seq analysis, rounding off the course with post-course surveys and quizzes.

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