Course

Introduction to the Biology of Cancer

Johns Hopkins University

Embark on a journey to comprehend the intricacies of cancer with the "Introduction to the Biology of Cancer" course offered by Johns Hopkins University. This open course delves into the molecular biology of cancer, highlighting oncogenes, tumor suppressor genes, and the biologic hallmarks of cancer. Gain insights into the incidence, etiology, and major types of cancer globally, encompassing lung, breast, colon, prostate, liver, and stomach cancers. Uncover the pivotal role of genetics in cancer risk and growth, and explore the ten cellular hallmarks of cancer. Furthermore, delve into the daunting realm of metastasis, understanding its process and staging, while also discovering the significance of imaging in cancer screening, diagnosis, and treatment. Comprehend the various treatment modalities and their application in the context of different cancers, along with an exclusive focus on liver and prostate cancers in the Honors lessons. This course equips learners with a foundational understanding of cancer biology and treatment, serving as a valuable resource for comprehending cancer development, diagnosis, and treatment.

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Introduction to the Biology of Cancer
Course Modules

The course comprises six modules. Module 1 covers the incidence and etiology of cancer, while Module 2 delves into the genetics of cancer. Module 3 explores the ten cellular hallmarks of cancer, and Module 4 focuses on metastasis. Imaging in oncology is covered in Module 5, and Module 6 details various cancer treatments, with a special emphasis on liver cancer.

Incidence and Etiology of Cancer

Embark on an exploration of the incidence and etiology of cancer, gaining insight into the common cancers worldwide. Learn about the risk factors, grading, and Honors lessons focusing on liver and prostate cancers.

Genetics of Cancer

Understand the genetic underpinnings of cancer, including genetic variation, mutation, and the two-hit hypothesis. Delve into the role of genomic instability in cancer development.

Ten Cellular Hallmarks of Cancer

Explore the ten cellular hallmarks of cancer, comprehending the defining features of cancer cells and their implications in cancer development and progression.

Metastasis: The Real Killer

Uncover the complexities of metastasis, including TNM staging and the metastatic process. Gain insight into the ecological paradigm driving cancer cell metastasis from the primary tumor.

Imaging in Oncology

Discover the crucial role of imaging in clinical oncology, different types of imaging, and its support in cancer treatment, including the theory of oligometastasis.

Treatment

Delve into the diverse types of cancer treatments, clinical trials, and gain in-depth knowledge of liver cancer, encompassing its incidence, risk factors, staging, and treatment modalities.

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